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Biochemistry 43:1295512963

Vascular barrier protective effects of phlorotannins on HMGB1-mediated proinflammatory responses in vitro and in vivo

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Results showed a significant reduction in 5-HT levels in the TMAO + MPTP group compared to the MPTP group, indicating that TMAO diminishes neurotransmitter 5-HT levels, influencing the onset of PD